Enterprise Architect - Pharma Commercial at Genentech

Job description

Enterprise Architect - Pharma Commercial The Opportunity The Enterprise Architect - Pharma Commercial acts as the strategic bridge between the central Strategy, Portfolio & Governance (SPG) organization and Pharma Medicines. Operating within a federated model, you will orchestrate the global Pharma Commercial architecture network. Your primary focus will be translating business goals into adaptable, future-ready technology roadmaps across Market Access, Marketing, Customer Engagement, Analytics, and Commercial Operations. Once hired, the actual title will be Domain Architect – Pharma Commercial. Key Responsibilities Partner with Business and Roche Digital Technology (RDT) leadership to align global and regional business priorities with multi-year technology roadmaps and target-state architectures. Lead a federated network of embedded domain and solution architects. Establish shared strategic priorities, technology guardrails, and security/privacy standards. Drive architectural success for high-impact initiatives, including customer engagement modernization (e.g., Elevate, AI-driven content supply chains, and patient strategy). Develop and maintain commercial capability maps, target-state architectures, and technology inventories using tools like ArchiMEDES (SAP LeanIX). Guide investment decisions alongside Portfolio Management by evaluating strategic impacts, maximizing platform reuse, and managing technical debt to optimize total cost of ownership (TCO). Monitor emerging commercial technology trends and evaluate vendors to ensure a future-ready, optimized architecture. Collaborate with legal, compliance, and cybersecurity teams to ensure all commercial architectures strictly adhere to global data privacy regulations (e.g., GDPR, HIPAA) and patient data governance standards. Who You Are Bachelor’s degree in Engineering, IT, or Science. A Master’s degree is preferred. At least 10 years of direct experience in IT and enterprise/domain architecture, with a proven history of migrating legacy commercial systems to modern, cloud-native ecosystems. At least 5 years of experience in the biotech/pharma industry. Proven track record navigating and influencing within a complex, matrixed, or federated global organization. Deep domain expertise in global Pharma Commercial operations (Field CRM, Omnichannel Marketing, Market Access, and Patient Services). Technical Skills Strong expertise in modern digital tech stacks (e.g., Veeva, Salesforce) and high-volume integrations between front- and back-office systems. Proficiency in architecting scalable data products, MDM (Master Data Management), and AI-driven commercial data solutions. Highly skilled in designing pragmatic target-state architectures and evolving roadmaps aligned with complex business needs. Familiarity with enterprise architecture frameworks (e.g., TOGAF) and agile/product-led delivery methodologies. Leadership & Communication Demonstrated ability to cultivate, inspire, and lead networks of architects via influence rather than authority (without direct reporting lines). Serves as a trusted advisor to senior leadership with strong executive presence and business acumen. Excels at translating complex architectural strategies into relatable, business-centric narratives that balance enterprise coherence with local agility. The expected salary range for this position based on the primary location of South San Francisco, CA is $170,800 - $317,200. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are not available for this job posting. #RDT2026 Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company s policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .

Requirements

Must-haves

Enterprise Architect - Pharma Commercial
Once hired, the actual title will be Domain Architect – Pharma Commercial.
Partner with Business and Roche Digital Technology (RDT) leadership to align global and regional business priorities with multi-year technology roadmaps and target-state architectures.
Lead a federated network of embedded domain and solution architects. Establish shared strategic priorities, technology guardrails, and security/privacy standards.
Drive architectural success for high-impact initiatives, including customer engagement modernization (e.g., Elevate, AI-driven content supply chains, and patient strategy).
Develop and maintain commercial capability maps, target-state architectures, and technology inventories using tools like ArchiMEDES (SAP LeanIX).
Guide investment decisions alongside Portfolio Management by evaluating strategic impacts, maximizing platform reuse, and managing technical debt to optimize total cost of ownership (TCO).
Monitor emerging commercial technology trends and evaluate vendors to ensure a future-ready, optimized architecture.
Collaborate with legal, compliance, and cybersecurity teams to ensure all commercial architectures strictly adhere to global data privacy regulations (e.g., GDPR, HIPAA) and patient data governance standards.
At least 10 years of direct experience in IT and enterprise/domain architecture, with a proven history of migrating legacy commercial systems to modern, cloud-native ecosystems.
At least 5 years of experience in the biotech/pharma industry.
Proven track record navigating and influencing within a complex, matrixed, or federated global organization.
Deep domain expertise in global Pharma Commercial operations (Field CRM, Omnichannel Marketing, Market Access, and Patient Services).
Technical Skills
Strong expertise in modern digital tech stacks (e.g., Veeva, Salesforce) and high-volume integrations between front- and back-office systems.
Proficiency in architecting scalable data products, MDM (Master Data Management), and AI-driven commercial data solutions.
Highly skilled in designing pragmatic target-state architectures and evolving roadmaps aligned with complex business needs.
Familiarity with enterprise architecture frameworks (e.g., TOGAF) and agile/product-led delivery methodologies.
Leadership & Communication
Demonstrated ability to cultivate, inspire, and lead networks of architects via influence rather than authority (without direct reporting lines).
Serves as a trusted advisor to senior leadership with strong executive presence and business acumen.
Excels at translating complex architectural strategies into relatable, business-centric narratives that balance enterprise coherence with local agility.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .

Nice-to-haves

Bachelor’s degree in Engineering, IT, or Science. A Master’s degree is preferred.

Application prep

Use the role’s language and application details while tailoring your materials.

Keywords to mirror

aiagile

Platform: workday
Effort: long