Principal Research Scientist I - Process Engineering
AbbVie· Biopharmaceuticals· Aug 10, 2026 · 3mo agoPosted 78 days ago
North Chicago, IL, United States
In office
Full-time
Principal
$190K–$256K est.
14+ years exp
Before you apply
Ghost Signal:
Open 78 days.
Job description
Are you a passionate engineer who thrives at the intersection of science, innovation, and impact? AbbVie's Research and Development Process Engineering team is on the front lines of transforming cutting-edge science into life-changing medicines — and we're looking for a Principal Research Engineer I /II to help us push the boundaries of what's possible in drug product development. Join us at our North Chicago, IL hub and be part of something bigger.
This isn't just a role — it's an opportunity to shape the future of drug manufacturing . You'll bring your proven project leadership in drug product development to drive synthetic molecule candidates from concept to commercial-ready processes, making real decisions that accelerate medicines to patients who need them most.
You'll be a master of drug product manufacturing platforms — direct compression, wet & dry granulation, hot melt extrusion, tableting, encapsulation, and film coating — and you'll apply your deep understanding of powder material properties to unlock new levels of manufacturability and product performance. When challenges arise, you're the person who steps up to troubleshoot complex process and material issues with creativity and rigor. And when it's time to go big, you'll translate bench-scale breakthroughs into pilot plant realities through expert scale-up execution .
At AbbVie, we celebrate bold ideas, encourage experimentation, and give talented engineers the resources and autonomy to actually innovate . If you're ready to raise the bar, lead with influence, and leave your mark on some of the world's most important medicines — we want to hear from you.
Key responsibilities include:
• Lead drug product manufacturing process early phase development for synthetic molecule development candidates within the AbbVie pipeline.
• Collaborate with development CMC teams to ensure manufacturing processes are aligned with intended commercial manufacturing sites.
• Advance scientific expertise within the function — mentoring peers and influencing senior leadership with your expert insights.
• Drive the development of technologies and scientific innovations that expand AbbVie's small molecule formulation capabilities.
• Partner cross-functionally to build strategies that directly power AbbVie's drug discovery and development programs.
• Champion compliance with AbbVie's safety, quality, and regulatory standards.
• BS (+14 yr experience) MS (+12 yr. experience) or PhD (+6 yr experience) in Chemical Engineering, or equivalent scientific/engineering degrees
• Strong project leadership experience for drug product development.
• Advanced understanding drug product manufacturing platforms with direct compression, wet & dry granulation, and hot melt extrusion which include tableting, encapsulation and film coating.
• Advanced understanding of powder material properties and their impact on drug product manufacturability and final product performance.
• Ability to apply/interpret models during drug product development to optimize development.
• Experience writing regulatory submissions and generating the data required to gain approval
• Demonstrated ability to troubleshoot process/material issues.
• Apply techniques to scale-up the development process to pilot plant equipment.
• Displays technical awareness in various aspects of drug development, adherence to rigorous scientific methods, and commitment to the scientific process.
• Strong drive for learning new techniques and technologies.
• Excellent oral and written communication skills.
• Demonstrated ability to work collaboratively in a cross-functional team setting.
Preferred:
• Drug Substance Crystallization development knowledge
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of thisposting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless anduntil paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit abbvie.com
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
abbvie.com
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Benefits
Benefits detected in the listing.
Dental
Vision
401(K)
Paid Time Off