Sr. Clinical Operations Manager
House Rx· Hospital & Health Care· Apr 17, 2026 · 6mo agoPosted 193 days ago
United States
In office
Full-time
Manager
$150K–$190K
8+ years exp
Before you apply
Ghost Signal:
Open since April 17, 2026 — 193 days, and still accepting applications.
Job description
House Rx is on a mission to make specialty medications more affordable and accessible for patients suffering from chronic illnesses like cancer and autoimmune disorders. We provide clinics with specialized technology and support from pharmacists and care coordinators to dispense medication directly to their patients, known as medically integrated dispensing (MID).
This work will directly contribute to the company’s mission of making specialty medications affordable and accessible for patients— keep reading to learn more about the role, our team, and why House Rx is the right next step in your career! Applicants must be based in the United States and have permanent US work authorization.
About the role
We are seeking an experienced and dynamic Senior Clinical Operations Manager to lead our customer operations by balancing key responsibilities in Customer Success and Pharmacy Operational Management.
Clinical Operations Managers (COMs) are specialty pharmacy SMEs with deep operational understanding. COMs are the primary customer operational contact, managing workflow operations through daily interactions with clinic staff and resolving escalations cross-functionally, both inside the clinic and across House Rx’s internal team. A COM balances problem solving and rolling up their sleeves in the workflow.
This role includes a significant people leadership component, coupled with the executive presence necessary to work with physician leaders at our clinics. In addition to overseeing daily operations, the COM is involved in quality audits and analyzing metrics in order to identify gaps - diagnosing the what/why and building effective action plans to get and stay ahead of issues. COMs also work closely with our Customer Success Managers, providing operational metrics for Monthly/Quarterly Business Reviews and working on optimization initiatives.
The ideal candidate has specialty pharmacy experience and moved into a broader business role over time. This candidate thrives on providing great customer service, working flexibly in a fast moving and sometimes ambiguous environment, and leading a team. As a People Leader, the COM will be responsible for driving individual and team performance through consistent coaching, real-time feedback, and active mentorship - a hands-on manager for our hourly workforce. This candidate thrives in a fast-paced environment, focusing on developing the skills of our frontline hourly associates while ensuring key service metrics are met and career paths are forged.
The COM role continues to evolve, allowing room for new ideas and the opportunity to shape what the role and the company look like moving forward. This is a high visibility role, with significant autonomy and frequent interaction with our clinical leadership team. COMs report to our VP of Clinical Operations.
This role will be remote-based and require travel to customer sites. Most of our COMs travel ~20% of the time, but this may be higher or lower depending on the portfolio of customers (will be discussed further throughout the interview process).
Key Responsibilities:
Operational Management:
People Management: Oversee daily operations, manage schedule adherence, and maintain a high-energy culture. Balance operational efficiency with a supportive employee experience, ensuring our team is engaged, productive, and equipped to handle high call volumes.
Proactive Monitoring: Regularly monitor communication channels, task queues, and documentation to identify potential operational gaps before they impact customers. Aim for zero emergent escalations.
Issue Resolution: Distinguish between program-related and operational issues, addressing customer expectations independently when possible, and escalating Clin Ops-related concerns as needed. Take ownership of investigations and ensure swift resolutions, always keeping an eye to closing the loop and next steps.
Operational Alignment: Participate in operational reviews with internal teams, maintaining a high alignment score based on cross-functional feedback regarding clarity and execution. Work on optimization initiatives.
Customer Request Evaluation: Lead assessments of the operational implications of customer requests, working toward mutually viable and effective solutions.
Financial Growth: Support Customer Success Managers in identifying opportunities for financial growth initiatives within customer programs.
Customer Success:
Relationship Building: Establish and maintain strong, collaborative relationships with key stakeholders, including dispensers, clinic staff, financial personnel, providers, and executives. Your ability to connect with stakeholders at all levels is essential.
Effective Communication: Tailor communication to suit various audiences, ensuring clarity and alignment. From engaging with prior authorization staff on operational details to contributing to strategic insights in Quarterly Business Reviews (QBRs), your communication should be both clear and impactful.
Objection Handling: Proactively address concerns and objections raised by stakeholders. Utilize reassuring and confident communication techniques to advocate for our program and ensure satisfaction across all organizational levels.
Qualifications:
Experience: 8+ years of experience with a minimum of 3-5 years managing specialty pharmacy operations or a similar role, with a demonstrated track record of success in customer relations and operational management. Experience/knowledge of the pharmacy space is required; specialty pharmacy experience is strongly preferred
Skills: Strong relationship-building and communication skills, with the ability to adapt communication styles to various audiences; excellent time management skills with the ability to manage effectively across multiple customers.
Analytical Abilities: Proficient in analyzing operational metrics to identify/diagnose issues.
Operational Proficiency: Experience in operational oversight, with a focus on issue resolution and process optimization.
Salary Range: Senior COM: $150,000-190,000
This range represents the low and high end of the anticipated base salary/wage. The actual base salary/wage will depend on several factors, including experience, knowledge, and skills. Actual compensation packages may include other elements such as equity, paid time off and benefits.
Why You Should Join Our Team
A career at House Rx offers the chance to work with a talented group of entrepreneurs, healthcare professionals, and technology builders who are passionate about improving specialty care and making it easier for patients to access the medication that they need.
At House Rx, we strive to build and maintain an environment where employees from all backgrounds are valued, respected and have the opportunity to succeed. You'll find a culture that supports open communication, embracing failure as a learning opportunity, and always being open to new ideas—no matter how radical. We are a remote-first company, however, some pharmacy operations roles require onsite clinic presence. We’re committed to creating a positive and collaborative culture to achieve our mission, all while supporting our team members in all aspects of their lives—at home, at work and everywhere in between.
In particular, we offer:
Flexible work hours and flexible paid time off
Work remotely
Generous parental leave
Comprehensive healthcare, vision and dental benefits
Competitive salary and equity stake
We’re backed by forward-thinking investors committed to transforming healthcare, including Bessemer Venture Partners, First Round Capital, LRV Health, NEA, Town Hall Ventures, Khosla Ventures, Maverick Ventures, 1984.vc, and Character
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Benefits
Benefits detected in the listing.
Dental
Vision
Paid Time Off
Parental Leave