Technical Program Manager (DDMR)
Isomorphic Labs· Biotechnology· Oct 9, 2026 · 19d ago
Cambridge, MA
Hybrid
Full-time
Mid
$115K–$166K est.
Job description
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.
The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.
Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.
The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.
About Iso
Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.
Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.
We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.
Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.
Your impact
As part of the ongoing expansion of our Drug Design and Medical Research (DDMR) function, we are looking to recruit our first Technical Program Manager to our Cambridge, MA office.
As a member of the Technical Program Management team you will be responsible for facilitating all aspects of small molecule drug discovery program management for Cambridge programs, providing hands-on support to our AI-first Drug Design programs, ensuring smooth integration with our London office. You will work in alignment with the drug design teams in Cambridge and liaise with key internal stakeholders across finance, legal, alliance management and AI/tech.
If you are an organised, skilled and ambitious individual looking to take the next step in your career, joining Isomorphic Labs now will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development.
What you will do
As a member of the TPM team you will be responsible for supporting DDMR with program planning, dynamically monitoring timelines, action tracking, risk reporting, driving effective meetings and stakeholder management
You will manage and monitor program budgets with respect to forecasting and actual spend to support the program team, DDMR and TPM team as well as report out to senior stakeholders
You will provide help to program teams to effectively liaise with CROs and other external providers/partners, helping with contract reviews and processing
You will help to build and embed processes and operating systems, ensuring integration and alignment across Isolabs
Skills and qualifications
Essential:
At least a BSc in Biology, Chemistry or related discipline
Proven industry experience in contributing to, managing or leading early stage / discovery small molecule and / or glue and / or peptide drug design programs
Understanding of small molecule / glue / peptide drug discovery & development processes in the context of project & program planning, and governance
Experience of managing budgets, including planning, forecasting, monitoring, troubleshooting and working to identify efficiencies
Experience of operational program management processes
Experience with program risk management
Experience supporting teams in fast-paced and constantly changing environments
Ability to adaptively interact and confidently communicate with diverse key stakeholders
Patient, organised and detail-oriented
Nice to have:
Advanced degree in Biology, Chemistry or related discipline
Program management qualification
Experience of working in an ML drug discovery environment
Working with Jira and / or confluence or other program management software
Culture and values
We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.
Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.
Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.
Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.
Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.
Creating an extraordinary company
We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.
We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.
Hybrid working
It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.
Please note that when you submit an application, your data will be processed in line with our privacy policy .
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