Principal Programmer Analyst
Gsk· Healthcare/Pharmaceuticals· Oct 13, 2026 · 14d ago
Upper Providence, PA
Hybrid
Full-time
Principal
$141K–$216K est.
Job description
Principal Programmer Analyst
We are seeking a Principal Programmer Analyst to join our Clinical Programming team, contributing to pipeline delivery across complex and pivotal studies. This role operates within an agile, squad-based environment, where you will lead study delivery, collaborate with cross-functional teams, and act as a technical mentor to ensure high-quality and timely outputs. Working closely with stakeholders across clinical, statistical, and operational functions, you will play a key role in bridging scientific requirements with technical solutions, supporting the successful execution of clinical development programmes within a global setting.
We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.
We embrace modern work practices; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.
Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK
In this role you will
Independently lead programming activities for one or more studies, ensuring development, maintenance, and validation of complex analysis packages
Foster quality assurance by ensuring programming activities adhere to standards such as Good Programming Practices and CDISC
Mentor junior programmers by providing guidance and support in technical programming tasks and industry best practices
Lead programming support for regulatory interactions (e.g., EMA, FDA)
Identify gaps and inefficiencies and recommend and implement innovative solutions aligned with standards and best practices
Establish and uphold governance frameworks, identify risks early and devise mitigation plans, ensuring timely escalation
Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:
Bachelor’s degree in Mathematics, Computer Science, or a related discipline
Five or more years if experience with at least one programming language and ability to evaluate and select appropriate tools or languages for specific tasks
Three or more years of experience working in the pharmaceutical/biotech industry with advanced understanding of clinical trials and therapeutic areas, applied to enhance programming outputs and decision-making
Experience leading discussions on programming strategies, displays, and custom programs
Experience implementing principles of governance, quality control, and compliance with regulatory requirements and programming standards
Preferred Qualifications:
Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:
Experience guiding others in the use of Artificial Intelligence/Machine Learning (AI/ML) tools or applying these tools to improve efficiency
Experience contributing to internal technical discussions, forums, or external technical organizations
Application of critical thinking to implement standards and collaborate with stakeholders where deviations are required
Ability to articulate complex technical information effectively to both technical and non-technical stakeholders
Experience contributing to department strategies and key technical initiatives through working groups or sub-teams
Demonstrated networking and collaboration across departments, divisions, and external partners
Experience facilitating integration across matrix teams and contributing to planning and execution of programming activities
Experience guiding teams and individuals, fostering continuous improvement, collaboration, and innovation
Demonstrated proficiency in R.
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D .
Skills
Agile Leadership, Agile Methodology, Clinical Development, Data Engineering, Data Science, Influencing Without Authority, Learning Agility, Problem Solving, Statistical Programming
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments gsk.com
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at openpaymentsdata.cms.gov
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