Senior Manager, Global E2E Product Supply Planning & RCCP at BioMarin Pharmaceutical Inc

Job description

Who We Are BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions. Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions like achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and a number of forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, available options. More recently, with the close of the Amicus acquisition, our portfolio has expanded to include therapies for Fabry disease and Pompe disease, expanding our ability to reach more people living with rare genetic conditions. Our success comes from our unwavering commitment to excellence, our deep understanding of patient needs, our scientific expertise, and our world-class manufacturing capabilities. At the heart of BioMarin is a dedicated team of the brightest minds in the industry working together to deliver innovative therapies to patients and families around the world. About Technical Operations BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Preference for candidates who can work Hybrid in San Rafael, CA, but Remote possible. ROLE PURPOSE The Senior Manager, Global E2E Product Supply Planning & RCCP serves primarily as the End-to-End Product Supply Leader for assigned highly complex products and portfolio segments. Approximately 70% of the role is dedicated to developing, governing, and executing integrated product supply strategies and plans across Drug Substance, Drug Product, and Finished Goods. The role orchestrates internal manufacturing sites, CMOs/CDMOs, distribution partners, regions, and markets to protect patient supply and balance service, inventory, cost, capacity, and risk outcomes Approximately 30% of the role is dedicated to developing, implementing, governing, training, and continuously improving Rough-Cut Capacity Planning within the 0– 36 month Integrated Business Planning horizon. The role partners closely with Network Capacity Planning to translate product-level requirements into decision-ready capacity insights. Network Capacity Planning retains ownership of network capacity plans and longer-range capacity strategy ROLE ALLOCATION AND OPERATING MODEL • E2E Product Supply Planning leadership for highly complex assigned products or portfolio segments • RCCP process ownership and capability enablement across the 0– 36 month IBP horizon. • The percentage allocation describes the expected emphasis of the role and may flex temporarily based on launches, disruptions, annual planning cycles, or RCCP deployment milestones. • The role is an expert individual contributor and operates through shared accountability and influence rather than direct authority. E2E PRODUCT SUPPLY PLANNING ACCOUNTABILITIES Product Supply Strategy and Integrated Planning • Serve as the E2E Product Supply Leader for assigned highly complex products across launch, growth, maturity, and sunset stages. • Develop and govern credible global supply strategies and executable plans across Drug Substance, Drug Product, and Finished Goods. • Integrate demand, supply, inventory, capacity, quality, regulatory, financial, lifecycle, and market considerations into an aligned course of action. • Maintain clear planning assumptions, decision rights, scenarios, risks, actions, and governance pathways. • Ensure approved decisions and changing business conditions are reflected accurately in SAP IBP and related planning outputs. Product Supply Performance and Inventory • Drive shared accountability for product availability, customer service, inventory health, supply continuity, excess and obsolete inventory, and plan execution. • Develop inventory strategies and recommend positioning, targets, deployment, and risk-protection actions across internal sites, CMOs/CDMOs, distribution centers, and markets. • Monitor performance, identify root causes and emerging trends, and coordinate corrective or preventive actions with accountable partners. • Balance patient supply, service, inventory, working capital, cost, resilience, and execution feasibility when forming recommendations. Risk, Scenarios, and Decisions • Anticipate systemic, emerging, and second-order supply risks across interconnected product and network dependencies. • Lead complex scenario planning, contingency evaluation, supply prioritization, and trade-off analysis. • Synthesize incomplete or conflicting information into clear options, implications, recommendations, and decision timing. • Make product-level planning decisions within established governance and escalate enterprise-level constraints or unresolved trade-offs. • Lead follow-through on approved mitigation plans, accountabilities , milestones, and outcomes. Network and Stakeholder Orchestration • Orchestrate planning and execution across internal manufacturing sites, CMOs/CDMOs, Network Planning, Network Capacity Planning, Regional Supply Chain Planning, Quality, Regulatory, Logistics, Finance, and Commercial partners. • Create alignment across stakeholders with competing priorities without relying on direct authority. • Represent Global E2E Product Supply Planning in Supply Review, S&OP/IBP, PSCO, VST, launch, lifecycle, and other governance forums, as applicable. • Translate product strategy and market requirements into clear supply implications and coordinated cross-functional actions. Communication, Change, and VUCA Leadership • Distill complex evidence into concise executive narratives, clear choices, and decision-ready recommendations. • Tailor communication for executive, technical, operational, regional, market, and external-partner audiences. • Lead product-supply changes by clarifying the case for change, stakeholder impacts, readiness, resistance, communications, adoption, and reinforcement. • Create direction without false certainty and help stakeholders navigate volatility, uncertainty, complexity, and ambiguity. • Communicate difficult decisions , trade-offs, and uncertainty with transparency, presence, empathy, and precision. RCCP ACCOUNTABILITIES RCCP Process Development and Governance • Own the design, implementation, governance, sustainment, and continuous improvement of RCCP across the 0– 36 month IBP horizon. • Define RCCP standards, methods, assumptions, capacity measures, time buckets, tolerance thresholds, scenarios, roles, decision rights, and escalation pathways. • Maintain RCCP playbooks, process maps, calendars, templates, controls, standard work, and maturity roadmap. • Integrate RCCP inputs, scenarios, risks, and actions into Supply Review, S&OP/IBP, AOP, LRP, portfolio, and product governance cycles. • • Partnership with Network Capacity Planning • Maintain a strong operating partnership with Network Capacity Planning and align product-level requirements with network-level capacity assumptions and plans. • Translate product demand, supply, inventory, launch, lifecycle, and risk assumptions into aggregate capacity requirements. • Jointly develop scenarios to identify emerging constraints, capacity opportunities, timing gaps, and mitigation options within the IBP horizon. • Clarify ownership and handoffs between Product Supply Planning and Network Capacity Planning to prevent gaps, duplication, or conflicting assumptions. • Preserve Network Capacity Planning ownership of network capacity plans and longer-range capacity strategy. RCCP Systems, Data, Analytics, and AI • Own business-process and functional requirements for RCCP capabilities in SAP IBP and supporting solutions. • Partner with Digital, Data, Technology, and planning teams on design, configuration, testing, validation, deployment, releases, and enhancements. • Define required capacity master data, resource structures, planning parameters, calculations, workflows, reports, alerts, and scenario outputs. • Establish governance for data quality, model integrity, assumptions, traceability, and user access. • Use analytics and AI-enabled tools to improve scenario development and decision support while applying appropriate validation , confidentiality, governance, and human judgment. RCCP Training, Change Management, and Adoption • Develop and deliver role-based RCCP training, practical exercises, job aids, facilitator materials, and reference guides. • Establish onboarding, refresher learning, proficiency expectations, coaching, and an RCCP community of practice. • Lead the people side of RCCP implementation by building sponsorship, assessing readiness and stakeholder impact, anticipating resistance, and reinforcing adoption. • Measure process adoption and capability maturity and adjust training, communication, and deployment approaches based on feedback and performance. DECISION AUTHORITY AND ACCOUNTABILITY Own product-level supply planning decisions within agreed governance and lead recommendations for complex strategic trade-offs. • Recommend inventory positioning, deployment, supply prioritization, sourcing, contingencies, and lifecycle actions for assigned products. • Own RCCP process standards, methodologies, governance, business requirements, training standards, adoption measures, and improvement roadmap. • Lead RCCP scenario framing and recommend actions within the 0– 36 month IBP horizon. • Escalate material capacity constraints, cross-product trade-offs, unresolved assumption conflicts, and decisions outside delegated authority. • Do not own network capacity plans, capital strategy, manufacturing footprint strategy, or longer-range network capacity strategy. KEY INTERFACES Primary RCCP Partnership • Network Capacity Planning • Manufacturing Operations Internal • Demand Planning and Regional Supply Chain Planning • Network Planning, Manufacturing Operations, Site Planning, and Technical Operations • Quality, Regulatory Affairs, Procurement, Logistics, Finance, and Commercial • Portfolio, Launch, Product Strategy, Supply Review, S&OP/IBP, AOP, LRP, PSCO, and VST teams • Digital, Data, Technology, Analytics, Master Data, and SAP IBP teams External • Contract Manufacturing Organizations and Contract Development and Manufacturing Organizations • Logistics service providers and strategic supply partners • Technology and implementation partners, as applicable • KNOWLEDGE, SKILLS, AND BEHAVIORS • Knowledge • Advanced E2E product supply planning knowledge across Drug Substance, Drug Product, Finished Goods, inventory, capacity, distribution, lifecycle strategy, and external supply. • Deep understanding of complex biopharmaceutical networks, constraints, resilience, and enterprise trade-offs. • Advanced understanding of RCCP, aggregate capacity planning, IBP, S&OP, AOP, LRP, and the relationship between product supply plans and network capacity plans. • Knowledge of process design, governance, system implementation, data structures, change management, training, analytics, and responsible AI use. Skills • Frames ambiguous problems and designs complex scenarios involving interacting constraints and uncertain assumptions. • Synthesizes large or conflicting datasets into strategic choices and executive recommendations. • Influences senior stakeholders and facilitates difficult trade-offs without direct authority. • Designs scalable RCCP business processes, governance, standards, and system requirements. • Leads organizational change, builds sponsorship, anticipates resistance, and reinforces sustained adoption. • Designs and delivers effective training, facilitation, coaching, and capability-building experiences. Behaviors • Demonstrates enterprise mindset and prioritizes patient and business outcomes over local optimization. • Shows decision courage and transparent communication in ambiguous, high-impact situations. • Creates calm, clarity, and alignment during disruption or sustained uncertainty. • Adapts successfully in a VUCA environment and helps others navigate change. • Challenges assumptions constructively and combines standardization with sound business judgment. • Models learning agility, digital curiosity, collaboration, accountability, and ethical use of data and AI. REQUIRED QUALIFICATIONS • Bachelor's degree in Supply Chain Management , Engineering, Biotechnology, Operations Management, Life Sciences, Business, or a related discipline. • Minimum 7 years of relevant experience in product supply planning, supply planning, capacity planning, operations planning, IBP, or a related supply chain discipline within biotechnology, pharmaceuticals, life sciences, consumer healthcare, or another regulated industry. • Demonstrated experience leading global E2E product supply planning for complex products across internal manufacturing sites and external CMOs/CDMOs. • Experience developing, implementing, governing, or materially improving RCCP or capacity-planning processes within an IBP or S&OP environment. • Experience partnering with Network Capacity Planning, manufacturing, site planning, or an equivalent capacity-planning function. • Experience with SAP IBP or an equivalent advanced planning platform, including business requirements, testing, implementation, or enhancement activities. • Demonstrated experience with supply risk, inventory strategy, lifecycle planning, scenario analysis, and cross-functional decision support. • Strong change-management , communication, executive presentation, facilitation, training, and stakeholder-influence skills. • Ability to adapt successfully in a VUCA environment and communicate complex ideas clearly to varied audiences. • Demonstrated proficiency with AI-enabled tools, advanced analytics, business intelligence, and digital planning technologies. • Ability to critically evaluate AI-generated outputs, validate assumptions and data, protect confidential information, and apply appropriate human judgment and governance. • Working knowledge of cGMP, FDA expectations, and applicable regulatory requirements. PREFERRED QUALIFICATIONS • Master's degree, MBA, or another relevant advanced degree. • APICS, CSCP, CPIM, or equivalent professional certification. • Formal change-management , facilitation, training, or process-improvement certification. • Experience with biopharmaceutical launches, lifecycle transitions, constrained networks, and external manufacturing. • Experience leading SAP IBP, RCCP, digital planning, or planning-transformation initiatives. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Ireland Safety Responsibility Support the organisation’s commitment to environmental protection, injury prevention, and continual improvement of EHS management systems. Actively contribute to a safe and environmentally responsible workplace by identifying hazards, reporting incidents and participating in EHS initiatives and training. Ireland Safety Responsibility Support the organisation’s commitment to environmental protection, injury prevention, and continual improvement of EHS management systems. Actively contribute to a safe and environmentally responsible workplace by identifying hazards, reporting incidents and participating in EHS initiatives and training.

Requirements

Must-haves

E2E Product Supply Planning leadership for highly complex assigned products or portfolio segments
RCCP process ownership and capability enablement across the 0– 36 month IBP horizon.
The percentage allocation describes the expected emphasis of the role and may flex temporarily based on launches, disruptions, annual planning cycles, or RCCP deployment milestones.
The role is an expert individual contributor and operates through shared accountability and influence rather than direct authority.
Product Supply Strategy and Integrated Planning
Serve as the E2E Product Supply Leader for assigned highly complex products across launch, growth, maturity, and sunset stages.
Develop and govern credible global supply strategies and executable plans across Drug Substance, Drug Product, and Finished Goods.
Integrate demand, supply, inventory, capacity, quality, regulatory, financial, lifecycle, and market considerations into an aligned course of action.
Maintain clear planning assumptions, decision rights, scenarios, risks, actions, and governance pathways.
Ensure approved decisions and changing business conditions are reflected accurately in SAP IBP and related planning outputs.
Product Supply Performance and Inventory
Drive shared accountability for product availability, customer service, inventory health, supply continuity, excess and obsolete inventory, and plan execution.
Develop inventory strategies and recommend positioning, targets, deployment, and risk-protection actions across internal sites, CMOs/CDMOs, distribution centers, and markets.
Monitor performance, identify root causes and emerging trends, and coordinate corrective or preventive actions with accountable partners.
Balance patient supply, service, inventory, working capital, cost, resilience, and execution feasibility when forming recommendations.
Risk, Scenarios, and Decisions
Anticipate systemic, emerging, and second-order supply risks across interconnected product and network dependencies.
Lead complex scenario planning, contingency evaluation, supply prioritization, and trade-off analysis.
Synthesize incomplete or conflicting information into clear options, implications, recommendations, and decision timing.
Make product-level planning decisions within established governance and escalate enterprise-level constraints or unresolved trade-offs.
Lead follow-through on approved mitigation plans, accountabilities , milestones, and outcomes.
Network and Stakeholder Orchestration
Create alignment across stakeholders with competing priorities without relying on direct authority.
Represent Global E2E Product Supply Planning in Supply Review, S&OP/IBP, PSCO, VST, launch, lifecycle, and other governance forums, as applicable.

Nice-to-haves

None flagged.

Application prep

Use the role’s language and application details while tailoring your materials.

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